姓名:程博涵
职称:讲师
学位:博士
所在系:动物遗传育种与繁殖
研究方向:家禽遗传育种、表观遗传学
办公电话:
电子邮箱:bhcheng@neau.edu.cn
姓名:程博涵
职称:讲师
学位:博士
所在系:动物遗传育种与繁殖
研究方向:家禽遗传育种、表观遗传学
办公电话:
电子邮箱:bhcheng@neau.edu.cn
个人简介
1.教育状况
2006.09-2010.06:东北农业大学动物科学专业,学士
2010.09-2013.06:东北农业大学动物遗传育种与繁殖专业,硕士
2013.09-2017.06:东北农业大学动物遗传育种与繁殖专业,博士
2.工作经历
2017.09-2021.08 best365体育官网平台 讲师
2021.08-至今 best365体育官网平台 副教授
著作论文
代表性论文(通讯作者,第一作者,共同第一作者)
[1] CHEN Hong-yan, CHENG Bo-han, MA Yan-yan, ZHANG Qi, LENG Li, WANG Shou-zhi, LI Hui. HBP1 inhibits chicken preadipocyte differentiation by activating the STAT3 signaling via directly enhancing JAK2 expression. Journal of Integrative Agriculture, 2022, 21(6): 1740-1754.
[2] Qi Zhang, Bohan Cheng, Haixu Jiang, Huili Zhang, Hui Li. N6-methyladenosine demethylase ALKBH5: a novel regulator of proliferation and differentiation of chicken preadipocytes. Acta Biochimica et Biophysica Sinica, 2022, 54(1): 1-9.
[3] Xinyang Zhang, Bohan Cheng, Yanyan Ma, Yumeng Liu, Ning Wang, Hui Zhang Yumao Li, Yuxiang Wang, Peng Luan, Zhiping Cao, Hui Li. Genome-wide survey and functional analysis reveal TCF21 promotes chicken preadipocyte differentiation by directly upregulating HTR2A. Biochem Biophys Res Commun, 2022, 587:131-138.
[4] Xinyang Zhang, Bohan Cheng, Haixu Jiang, Chang Liu, Zhiping Cao, Peng Luan, Ning Wang, Hui Li. Transcription factor 21 promotes chicken adipocyte differentiation at least in part via activating MAPK/JNK signaling. Genes, 2021, 12 (12):1971.
[5] Bohan Cheng, Li Leng, Ziwei Li, Weijia Wang, Yang Jing, Yudong Li, Ning Wang, Hui Li, Shouzhi Wang. Profiling of RNA N6-Methyladenosine methylation reveals the critical role of m6A in chicken adipose deposition. Front Cell Dev Biol. 2021, 9:590468.
[6] Chunyan Wu, Chong Chen, Yumeng Liu, Hui Li, Bohan Cheng. Proteomic analysis of liver tissue between fat and lean broiler lines. Br Poult Sci. 2021, 62(2):211-218
[7] Lijian Wang, Li Leng, Ran Ding, Pengfei Gong, Chang Liu, Ning Wang, Hui Li, Zhi-Qiang Du, Bohan Cheng. Integrated transcriptome and proteome analysis reveals potential mechanisms for differential abdominal fat deposition between divergently selected chicken lines. J Proteomics. 2021, 241:104242.
[8] Cheng B, Zhang H, Liu C, Chen X, Chen Y, Sun Y, Leng L, Li Y, Luan P, Li H. Functional intronic variant in the retinoblastoma 1 gene underlies broiler chicken adiposity by altering nuclear factor-kB and SRY-related HMG box protein 2 binding sites. J Agric Food Chem. 2019, 67(35):9727-9737.
[9] Chen H, Liu C, Liu Y, Li H, Cheng B. Transcription factor HBP1: A regulator of senescence and apoptosis of preadipocytes. Biochem Biophys Res Commun. 2019, 517(2):216-220.
[10] Chen H, Liu C, Chen C, Su Z, Shu J, Zhang M, Li H, Cheng B. Bone morphogenetic protein 4 regulates immortalized chicken preadipocyte proliferation by promoting G1/S cell cycle progression. FEBS Open Bio. 2019, 9(6):1109-1118.
[11] 刘畅, 陈洪艳, 张琦, 张心扬,李辉,程博涵. N6-甲基腺嘌呤RNA修饰研究进展. 中国家禽, 2019, 41(14):50-54.
[12] 宿志勇, 姜海煦, 冷丽, 白雪,李玉茂,栾鹏,李辉,程博涵. 高、低脂系肉鸡饲料转化效率与消化系统相关性研究. 东北农业大学学报, 2021, 52(12):1-8.
3.在研课题
国家自然科学基金(青年科学基金项目):“鸡METTL14基因调控前脂肪细胞分化的机制研究”,24万,2020.01-2022.12,主持;
黑龙江省普通本科高等学校青年创新人才培养计划:“鸡BMP4基因在前脂肪细胞增殖中的功能研究”,10万,2018.08-2021.09,主持;
黑龙江省自然科学基金(优秀青年项目):“鸡前脂肪细胞分化中TCF21互作蛋白的鉴定及功能分析”,10万,2022.07-2025.07,主持。
教学工作
本科生课程:《分子生物学》、《分子生物学实验》
研究生课程:《动物分子遗传学》
科技奖励与其他
学术荣誉
东北农业大学“青年才俊”。
社会兼职
世界家禽学会中国分会会员;
《BMC Genomics》、《遗传》杂志审稿人